EM Fundamentals

SEPSIS

Goals and Objectives Goals Resident will be comfortable with initial evaluation and basic management of patients with sepsis, severe sepsis and septic shock Learning Objectives Resident will be able to define: SIRS criteria Sepsis Severe Sepsis* Septic Shock For patients presenting with sepsis, resident will be able to: List and describe rationale for initial laboratory and radiology testing including screening for: Infectious source Metabolic derangement (including lactate) End-organ damage List and describe indications for early interventions, including: Antibiotics (including type) IV fluids (including quantity) Source control List and describe indications for advanced interventions Vasopressors Inotropes Steroids Blood transfusion

Recommended Resources Prior to Conference Sepsis Protocol (UChicago MEROps) Sepsis FAQ (EMCrit) ProCESS Review (PulmCCM) Additional Resources Review Articles Severe Sepsis and Septic Shock (NEJM 2013) (pdf) Primary Literature EGDT / Rivers (NEJM 2001) (pdf) ProCESS (NEJM 2014) ARISE (NEJM 2014) Sepsis-3 (JAMA 2016) (full text) Study Reviews ProCESS (EMCrit) ProCESS (PulmCCM) ProCESS (The Bottom Line) ProCESS (ALiEM) ARISE (EMCrit) ARISE (PulmCCM) ARISE (The Bottom Line) Organizations Surviving Sepsis Campaign

Original Post by Eric Shappell on 11/18/2014
Reviewed by James Ahn on 12/02/2014
Last Updated by Eric Shappell on 03/25/2016 Contact / Feedback